GMP certified 12%/24% salinomycin premix made in China

GMP Certified 12%/24% Salinomycin Premix veterinary medicines Made in China Salinomycin is a polyether antibiotic from the group of ionophores. It exerts anticoccidial effect against all species known as causative agents of coccidiosis in poultry (Eimeria acervulina, E. maxima, E. necatrix, E. mivati, E. tenella, E. br

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GMP Certified 12%/24% Salinomycin Premix veterinary medicines Made in China
 

Salinomycin is a polyether antibiotic from the group of ionophores. It exerts anticoccidial effect against all species known as causative agents of coccidiosis in poultry (Eimeria acervulina, E. maxima, E. necatrix, E. mivati, E. tenella, E. brunetti) as well as in the other farm animals (E. meleagridis, E. meleagrimitis, E. bovis, etc.). It is active against Gram-positive microorganisms, some anaerobes and Serpulina (Treponema) hyodysenteriae. The biological activity of salinomycin is based on its ability to form lipophilic complexes with the monovalent alkaline ions, making the cellular membranes of coccidia permeable to the ions mentioned. In this way, the intracellular ion concentration in the parasite cells is disturbed and anticoccidial effect of the preparation is achieved. This action is manifested already at the earliest stage of coccidia development hindering the maturity of the schizonts and the development of merozoites. An additional influence is the impeded transport of carbohydrate and the active sporozoite glycolysis provoked by salinomycin. The administration of salinomycin with the feed to ruminants (with developed forestomachs) at the recommended concentrations improves the weight gain and the feed conversion efficiency of the animals (as a result of the influence on the microflora and microfauna in the forestomachs which leads to an increase in the concentration of propionic acid and a decrease in the concentrations of lactic acid and acetic acid and a diminution of methane eructation from the rumen). Salinomycin reveals a nutritive effect in the growing and fattening pigs as well (affecting positively the beneficial microflora in the digestive tract of the animals).

 

COMPOSITION

Salinopharm 12% premi

Salinomycin sodium

12 g

Excipients

up to 100 g

 

 

 

Product name

Salinomycin Premix 12%

Items

Specification

Appearance

yellow-brownish granules

Identification

Ethanol solution of the substance to be examined reacting with vanillin test solution shows red

Particle size

≥95% pass through a 24 mesh sieve

Loss on drying

≤8.0%

Heavy metals

≤0.0020%

Arsenic

≤0.0002%

Salinomycin A

>85.0%

Related impurity fill

peak area of single impurity ≤5.0%

 

peak area of total impurities ≤10.0%

Assay

Content of labeled amount 90.0%%~110.0%

 

Potency 120u/mg

Packing

25kg/bag

 

 

Salinomycin Premix 12% 

[Pharmacological action]This product belongs to polyether ionophore anti-coccidial drug, which its effect and mechanism are similar with monensin.It has an effect on the prevention of chicken coccidiosis caused by E.necatrix. Eimeria tenella, E.maxima, E.mivati, E.acervulinm and E.brunetti. It has also obviously effect on sporophyte, first and second generation schizont of chicken coccidiosis. In clinic, it is mainly used for poultry coccidiosis.

[Indication]It is mainly used for control and prevention of chicken coccidiosis.

Administration and Dosage: Mix with feed, calculated by Salinomycin: Chicken, mix 60g of Salinomycin in 1000kg of feed.

[Adverse Reaction]Used according to the recommended dosage, no adverse reaction.

[Withdrawal Period]5 days for chicken.

 

DOSAGE

SPECIES

Salinomycin sodium ppm

Salinopharm 12% premix g/ ton feed

Chickens for fattening

60

500

Pigs up to 60 kg

50

420

Pigs from 61 to 110 kg

25

210

Lambs and calves

10 - 30

84 - 250

Replacement layers up to 12 weeks of age

60

500

 

[Precaution]

  1. It is prohibited to use with Tiamulin, Oleandomycin and other anti-coccidia products.
  2. It is prohibited to feed adult turkeys and horses due to its toxicity.
  3. The concentration fed should be strictly controlled due to its narrow safe range.
  4. It is prohibited to feed chickens during laying eggs.

[Strength]100g:12g(12,000,000 units)

[Package]25kg

[Storage]Store in an airtight container and keep in a dry place.

[Expiration Date]2 years

GMP Certified 12%/24% Salinomycin Premix Veterinary Medicines Made in China

 

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